L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-formylbutyl]-, sulfate (2:1) (103476-89-7)

  Leupeptin (103476-89-7) is odorless white to off-white powder, soluble in Water , Methanol , Ethanol , Butanol , Dimethyl sulfoxide , insoluble in Ethyl acetate , Acetone , Chloroform , Hexane , etc. Leupeptin (103476-89-7) is also known as N-acetyl-L-leucyl-L-leucyl-L-argininal ; Leupeptin hemisulfate salt . It is a protease inhibitor which inhibits serine proteinases, plasmin, porcine, and cysteine proteinases. It does not inhibit α-chymotrypsin or thrombin. It decompounds to yield Carbon monoxide , oxides of Nitrogen , oxides of Sulfur , Carbon dioxide . It is often used during in vitro experiments when a specific enzymatic reaction is being studied. When cells are lysed, proteases are released. These proteases, if freely present in the lysate, would destroy any products from the reaction being studied, and make the experiment uninterpretable. The suggested concentration is 1-10 µM (0.5-1 µg/ml).