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Eplerenone (107724-20-9)

Identification
Name:Eplerenone
CAS:107724-20-9
Molecular Formula: C24H30O6
Molecular Weight: 414.49
InChI: InChI=1/C24H30O6/c1-21-7-4-14(25)10-13(21)11-15(20(27)28-3)19-16-5-8-23(9-6-18(26)30-23)22(16,2)12-17-24(19,21)29-17/h10,15-17,19H,4-9,11-12H2,1-3H3/t15-,16+,17?,19?,21+,22+,23-,24-/m1/s1
Molecular Structure: (C24H30O6) Pregn-4-ene-7,21-dicarboxylic acid,9,11-epoxy-17-hydroxy-3-oxo-,?- lactone,methyl ester,(7R,11R,17R)...
Properties
Melting Point: 241-243oC
Density:1.31g/cm3
Refractive index:1.587
Solubility:Very slightly soluble in water, with its solubility essentially pH dependent
In water, 2.1X10-3 mg/L at 25 deg C (est)
Appearance:White Solid
Specification:

?Eplerenone (CAS NO.107724-20-9), its Synonyms are 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, methyl ester ; Epoxymexrenone ; Inspra ; Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)- .

Color: White to off-white crystalline powder
Usage:

Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoi

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