| Identification | |
| Name: | Docetaxel |
| Synonyms: | Benzenepropanoicacid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester, [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-;Docetaxel Winthrop;Docetaxol;Docetaxolum;HSDB 6965;RP 56976;Taxotere; |
| CAS: | 114977-28-5 |
| Molecular Formula: | C43H53NO14 |
| Molecular Weight: | 807.88 |
| InChI: | InChI=1/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32?,33-,35-,41+,42-,43+/m0/s1 |
| Molecular Structure: | ![(C43H53NO14) Benzenepropanoicacid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-,12b-(acetyloxy)-12-(benzoyl...](https://img.guidechem.com/casimg/114977-28-5.gif) |
| Properties | |
| Transport: | 1544 |
| Density: | 1.37 g/cm3 |
| Stability: | Stable at normal temperatures and pressures. |
| Refractive index: | 1.618 |
| Alpha: | -36 o (C=0.74,ETOH) |
| Solubility: | 60 g/L |
| Appearance: | Off-white Cryst. |
| Specification: | Adverse side effects of Docetaxel (CAS NO.114977-28-5) includes tumour cells as well as hair follicles, bone marrow and other germ cells. Thus,common chemotherapy side effects such as alopecia occur; sometimes this can be permanent. |
| Packinggroup: | III |
| Usage: | Corresponds to the cancer drug taxotere. Influence on microtubule assembly. |
| Safety Data | |
| Hazard Symbols |
Xi:Irritant
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