| Identification | |
| Name: | L-Serine,O-(2-diazoacetyl)- |
| Synonyms: | L-Serine,diazoacetate (ester) (9CI); Serine, diazoacetate (ester), L- (6CI,8CI);Azaserin; Azaserine; CI 337; CN 15757; L-Azaserine; NSC 742;O-Diazoacetyl-L-serine; P 165 |
| CAS: | 115-02-6 |
| EINECS: | 204-061-6 |
| Molecular Formula: | C5H7 N3 O4 |
| Molecular Weight: | 173.15 |
| InChI: | InChI=1/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11) |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 3462 6.1/PG 3 |
| Flash Point: | °C |
| Boiling Point: | °Cat760mmHg |
| Density: | g/cm3 |
| Specification: |
Azaserine (115-02-6) is a glutamine analogue that irreversibly inhibits Gln: Phosphoribosyl Amidotransferase, which is involved in the biosynthesis of Inosine monophosphate (IMP), and also can be called O-Diazoacetyl-L-serine ; L-azaserine ; O-succinyl-L-homoserine and Serine, diazoacetate (ester) . |
| Report: |
IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 (1976),p. 73.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. |
| Packinggroup: | III |
| Flash Point: | °C |
| Storage Temperature: | 2-8°C |
| Safety Data | |
| Hazard Symbols |
T: Toxic
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