| Identification |
| Name: | 5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione,12,13-dihydro- |
| Synonyms: | 6,7,12,13-Tetrahydro-5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione;Arcyriaflavin A |
| CAS: | 118458-54-1 |
| Molecular Formula: | C20H11 N3 O2 |
| Molecular Weight: | 325.32 |
| InChI: | InChI=1/C20H11N3O2/c24-19-15-13-9-5-1-3-7-11(9)21-17(13)18-14(16(15)20(25)23-19)10-6-2-4-8-12(10)22-18/h1-8,21-22H,(H,23,24,25) |
| Molecular Structure: |
![(C20H11N3O2) 6,7,12,13-Tetrahydro-5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione;Arcyriaflavin A](https://img1.guidechem.com/chem/e/dict/14/118458-54-1.jpg) |
| Properties |
| Flash Point: | °C |
| Boiling Point: | °Cat760mmHg |
| Density: | 1.621g/cm3 |
| Refractive index: | 1.96 |
| Biological Activity: | Potent inhibitor of cdk4/cyclin D1 (IC 50 = 59 nM). Also active against CaM kinase II (IC 50 = 25 nM) but displays selectivity over several other kinases in vitro (IC 50 values for inhibition of PKA and PKC are > 2 and > 100 μ M respectively). Inhibits human cytomegalovirus (HCMV) replication in vitro (IC 50 = 200 nM). |
| Flash Point: | °C |
| Safety Data |
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