| Identification | |
| Name: | 1-Piperidinepropanol, a-bicyclo[2.2.1]hept-5-en-2-yl-a-phenyl-, hydrochloride (1:1) |
| Synonyms: | 1-Piperidinepropanol,a-5-norbornen-2-yl-a-phenyl-, hydrochloride (6CI,7CI,8CI);1-Piperidinepropanol, a-bicyclo[2.2.1]hept-5-en-2-yl-a-phenyl-, hydrochloride (9CI);Akineton hydrochloride;Akinophyl;NSC 170950;NSC 84989;a-(Bicyclo[2.2.1]hept-5-en-2-yl)-a-phenyl-1-piperidinepropanolhydrochloride; |
| CAS: | 1235-82-1 |
| EINECS: | 214-976-2 |
| Molecular Formula: | C21H29NO.HCl |
| Molecular Weight: | 347.97 |
| InChI: | InChI=1/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 101 deg C |
| Density: | g/cm3 |
| Water Solubility: | slightly soluble in water and alcohol |
| Solubility: | slightly soluble in water and alcohol |
| Appearance: | White, crystalline, odorless powder |
| Specification: |
Biperiden hydrochloride (1235-82-1) also can be called Akineton ; a-Bicyclo[2.2.1]hept-5-en-2-yl-a-phenyl-1-piperidinepropanol Hydrochloride ; -Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-ylpropan-1-ol hydrochloride ; a-5-Norbornen-2-yl-a-phenyl-1-piperidinepropanol Hydrochloride ;and 1-Bicycloheptenyl-1-phenyl-3-piperidinopropanol Hydrochloride . |
| Biological Activity: | Muscarinic receptor antagonist that displays some selectivity for the M 1 subtype (K i values are 0.48, 2.4, 3.9, 6.3 and 6.3 nM for M 1 , M 4 , M 3 , M 2 and M 5 receptors respectively). Alleviates extrapyramidal symptoms associated with antipsychotic drugs. Displays antiparkinsonian activity. |
| Color: | Crystals |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
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