| Identification | |
| Name: | Fulvestrant |
| Synonyms: | Faslodex;Estra-1,3,5(10)-triene-3,17-diol,7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7a,17b)-;ICI 182780;ZD 182780;ZD 9238;ZM 182780; |
| CAS: | 129453-61-8 |
| Molecular Formula: | C32H47F5O3S |
| Molecular Weight: | 606.77 |
| InChI: | InChI=1/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1 |
| Molecular Structure: | ![(C32H47F5O3S) Faslodex;Estra-1,3,5(10)-triene-3,17-diol,7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7a,1...](https://img.guidechem.com/casimg/129453-61-8.gif) |
| Properties | |
| Density: | 1.201 g/cm3 |
| Refractive index: | 1.521 |
| Solubility: | In water, 9.53X10-6 mg/L at 25 deg C (est) |
| Appearance: | white powder |
| Specification: |
?Fulvestrant (CAS NO.129453-61-8) is also named as 7alpha-(9-((4,4,5,5,5-Pentafluoropentyl)sulfinyl)nonyl)estra-1,3,5(10)-triene-3,17beta-diol ; CCRIS 8741 ; Faslodex ; HSDB 7658 ; ICI 182,780 ; ICI 182780 ; UNII-22X328QOC4 ; ZM 182780 .?Fulvestrant (CAS NO.129453-61-8) is white powder. |
| Biological Activity: | A high affinity estrogen receptor antagonist (IC 50 = 0.29 nM), devoid of any partial agonism both in vitro and in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30. |
| Color: | White powder ... the solution for injection is a clear, colorless to yellow, viscous liquid |
| Usage: | Antineoplastic (hormonal) |
| Safety Data | |
 |
|
