| Identification |
| Name: | Agomelatine |
| Synonyms: | Thymanax;N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide;S 20098;Valdoxan;Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-; |
| CAS: | 138112-76-2 |
| Molecular Formula: | C15H17NO2 |
| Molecular Weight: | 243.3 |
| InChI: | InChI=1/C15H17NO2/c1-11(17)16-9-8-13-5-3-4-12-6-7-14(18-2)10-15(12)13/h3-7,10H,8-9H2,1-2H3,(H,16,17) |
| Molecular Structure: |
![(C15H17NO2) Thymanax;N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide;S 20098;Valdoxan;Acetamide, N-(2-(7-methoxy-1-na...](https://img.guidechem.com/casimg/138112-76-2.gif) |
| Properties |
| Density: | 1.109g/cm3 |
| Appearance: | white solid |
| Specification: | Agomelatine , its CAS NO. is 138112-76-2, the synonyms are N-(2-(7-Methoxy-1-naphthalenyl)ethyl)acetamide ; N-(2-(7-Methoxy-1-naphthyl)ethyl)acetamide ; N-(2-(7-Methoxynaphth-1-yl)ethyl)acetamide ; S20098 ; Thymanax ; UNII-137R1N49AD ; Valdoxan ; Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)- . |
| Usage: | A melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytry. |
| Safety Data |
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