| Identification | |
| Name: | Irbesartan |
| Synonyms: | BMS 186295;SR 47436;2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one;1,3-Diazaspiro[4.4]non-1-en-4-one,2-butyl- 3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]-;Avapro;3-byty1-3-[p-(0-1H-tetrazol-5-y1-pheny1)benzy1],3-diazospiro[4,4]non-1-en-4-ketone;Aprovel;138402-11-6;Irbesartan (JAN/USAN);Avapro (TN); |
| CAS: | 138402-11-6 |
| Molecular Formula: | C25H28N6O |
| Molecular Weight: | 428.54 |
| InChI: | InChI=1/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30) |
| Molecular Structure: |  |
| Properties | |
| Transport: | HAZARD |
| Density: | 1.3 g/cm3 |
| Refractive index: | 1.689 |
| Solubility: | Insoluble |
| Appearance: | white crystalline powder |
| Specification: |
? Irbesartan , with CAS number of 138402-11-6, can be called 1,3-Diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-((2-(1H-tetrazol-5-yl)(1,1-biphenyl)-4-yl)methyl)- ; 1,3-Diazaspiro[4.4]non-1-en-4-one,2-butyl- 3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]- methyl]- ; Avapro ; 3-byty1-3-[p-(0-1H-tetrazol-5-y1-pheny1)benzy1],3-diazospiro[4,4]non-1-en-4-ketone ; 2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one . It is a?crystalline solid, used as?an angiotensin II type 1 (AII1)-receptor antagonist.?Irbesartan is also available in a combination formulation with a low dose thiazide diuretic, invariably Hydrochlorothiazide, to achieve an additive antihypertensive effect. |
| Storage Temperature: | Store in original container in a cool dark place. |
| Usage: | An angiotensin II type 1 (AII1)-receptor antagonist |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
|
 |
|
