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4-Isoxazolepropanoicacid, a-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo- (140158-50-5)

Identification
Name:4-Isoxazolepropanoicacid, a-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-
Synonyms:2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoicacid; ATPA
CAS:140158-50-5
Molecular Formula: C10H16 N2 O4
Molecular Weight: 228.25
InChI: InChI=1/C10H16N2O4/c1-10(2,3)7-5(8(13)12-16-7)4-6(11)9(14)15/h6H,4,11H2,1-3H3,(H,12,13)(H,14,15)
Molecular Structure: (C10H16N2O4) 2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoicacid; ATPA
Properties
Flash Point: 199.9°C
Boiling Point: 406.8°Cat760mmHg
Density:1.264g/cm3
Refractive index:1.529
Biological Activity: A selective and potent GluR5 kainate receptor agonist (K i = 4.3 nM), inactive at GluR6 (K i > 1 mM) and only weakly active at AMPA receptors (GluR1-4) and the kainate receptors KA-2 and GluR7 (K i values of 6 - 14 μ M). Also available as part of the Kainate Receptor Tocriset™ .
Flash Point: 199.9°C
Color: white
Safety Data