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2-Chloroadenosine (146-77-0)

Identification
Name:2-Chloroadenosine
Synonyms:Cl-Ado;6-Amino-2-chloropurine riboside;(2R,3R,4R,5R)-2-(6-amino-2-chloro-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;4-26-00-03725 (Beilstein Handbook Reference);2-(6-amino-2-chloro-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;Antibiotic AT 265B;Adenosine,2-chloro-;2-Chloroadenosinehemihydrate;
CAS:146-77-0
EINECS: 205-678-3
Molecular Formula: C10H12ClN5O4
Molecular Weight: 301.69
InChI: InChI=1/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
Molecular Structure: (C10H12ClN5O4) Cl-Ado;6-Amino-2-chloropurine riboside;(2R,3R,4R,5R)-2-(6-amino-2-chloro-purin-9-yl)-5-(hydroxymethy...
Properties
Transport:OTH
Density:2.19 g/cm3
Water Solubility:soluble in methanol
Solubility:soluble in methanol
Appearance:white powder
Biological Activity: Metabolically stable analog of adenosine that behaves as an adenosine receptor agonist (K i values are 300, 80 and 1900 nM for A 1 , A 2A and A 3 receptors respectively). Anticonvulsive in vivo .
Usage:

A selective A1-adenosine receptor agonist. Induces apoptosis

Safety Data
Hazard Symbols