| Identification |
| Name: | N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE |
| Synonyms: | GR 127935 HYDROCHLORIDE;N-[4-METHOXY-3-(4-METHYL-1-PIPERAZINYL)PHENYL]-2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)-1,1'-BIPHENYL-4-CARBOXAMIDE HYDROCHLORIDE;N-[4-METHOXY-3-(4-METHYLPIPERAZIN-1-YL)-PHENYL]-4-[2-METHYL-4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)PHENYL]BENZAMIDE;GR 127935 HYDROCHLORIDE HYDRATE;GR127935HCl;N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide;GR 127935;N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1'-biphenyl-4-carboxamide hydrochloride |
| CAS: | 148672-13-3 |
| Molecular Formula: | C29H31N5O3 |
| Molecular Weight: | 497.59 |
| InChI: | InChI=1/C29H31N5O3/c1-19-17-23(28-30-20(2)37-32-28)9-11-25(19)21-5-7-22(8-6-21)29(35)31-24-10-12-27(36-4)26(18-24)34-15-13-33(3)14-16-34/h5-12,17-18H,13-16H2,1-4H3,(H,31,35) |
| Molecular Structure: |
![(C29H31N5O3) GR 127935 HYDROCHLORIDE;N-[4-METHOXY-3-(4-METHYL-1-PIPERAZINYL)PHENYL]-2'-METHYL-4'-(5-METHYL-1,2,4-...](https://img.guidechem.com/structure/148672-13-3.gif) |
| Properties |
| Flash Point: | °C |
| Boiling Point: | °Cat760mmHg |
| Density: | 1.219g/cm3 |
| Refractive index: | 1.619 |
| Biological Activity: | Potent and selective 5-HT 1B/1D receptor antagonist (pK i values are 8.5 for both guinea pig 5-HT 1D and rat 5-HT 1B receptors). Displays > 100-fold selectivity over 5HT 1A , 5-HT 2A , 5-HT 2C receptors and other receptor types. Centrally active following oral administration. |
| Flash Point: | °C |
| Storage Temperature: | 2-8°C |
| Color: | white |
| Safety Data |
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