| Identification | |
| Name: | Ginkgolide B |
| Synonyms: | GinkgolideA, 1-hydroxy-, (1b)- (8CI);5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-3a-carboxyhexahydro-a5a,1,2,3,5,8-hexahydroxy-a3-methyl-, tri-g-lactone (8CI);9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione,3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-, [1R-(1a,3b,3aS*,4b,6aa,7aa,7ba,8a,10aa,11b,11aR*)]-;BN 52051;9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione,3-(1,1-dimethylethyl)hexahydro-4,7b,11-trihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11R,11aR)-; |
| CAS: | 15291-77-7 |
| Molecular Formula: | C20H24O10 |
| Molecular Weight: | 424.39856 |
| InChI: | InChI=1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3 |
| Molecular Structure: | ![(C20H24O10) GinkgolideA, 1-hydroxy-, (1b)- (8CI);5H-Dicyclopenta[b,c]furan-3,5a(6H)-diacetic acid, 6-tert-butyl-...](https://img.guidechem.com/casimg/15291-77-7.gif) |
| Properties | |
| Density: | 1.64 g/cm3 |
| Refractive index: | 1.65 |
| Water Solubility: | Soluble to 100 mM in DMSO and to 25 mM in Ethanol |
| Solubility: | Soluble to 100 mM in DMSO and to 25 mM in Ethanol |
| Appearance: | white crystal powder |
| Biological Activity: | Platelet-activating factor (PAF) receptor antagonist (K i = 1.3 μ M). Inhibits neutrophil degranulation and superoxide production in vitro and inhibits bronchoconstriction and is neuroprotective following oral administration in vivo . |
| Storage Temperature: | 2-8°C |
| Usage: |
Ginkgolide B (CAS NO.15291-77-7) is used for family of bioactive terpenes treating cardiovascular and cerebrovascular diseases. Specific platelet activating factor (PAF) antagonists. |
| Safety Data | |
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