| Identification | |
| Name: | Rofecoxib |
| Synonyms: | 3-(4-Methanesulfonylphenyl)-2-phenyl-2-buten-4-olide;3-Phenyl-4-[4-(Methylsulfonyl)phenyl]-2(5H)-furanone;4-(4-(Methanesulfonyl)phenyl)-3-phenyl-5H-furan-2-one;4-[(4-Methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone;Ceeoxx;Ceoxx;MK 0966;MK 966;Rhuma-cure;2(5H)-Furanone,4-[4-(methylsulfonyl)phenyl]-3-phenyl-;Vioxx; |
| CAS: | 162011-90-7 |
| Molecular Formula: | C17H14O4S |
| Molecular Weight: | 314.35 |
| InChI: | InChI=1/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 |
| Molecular Structure: | ![(C17H14O4S) 3-(4-Methanesulfonylphenyl)-2-phenyl-2-buten-4-olide;3-Phenyl-4-[4-(Methylsulfonyl)phenyl]-2(5H)-fur...](https://img.guidechem.com/casimg/162011-90-7.gif) |
| Properties | |
| Density: | 1.333 g/cm3 |
| Refractive index: | 1.619 |
| Solubility: | Sparingly soluble in acetone, slightly soluble in methanol and isopropyl acetate, very slightly soluble in ethanol, practically insoluble in octanol, and insoluble in water. In water, 472 mg/L at 25 deg C /Estimated/ |
| Appearance: | off-white (pale yellow) crystalline powder |
| Specification: |
?Rofecoxib (CAS NO.162011-90-7) is also named as 3-Phenyl-4-(4-(methylsulfonyl)phenyl))-2(5H)-furanone ; 4-(4-(Methylsulfonyl)phenyl)-3-phenyl-2(5H)-furanone ; 4-(p-(Methylsulfonyl)phenyl)-3-phenyl-2(5H)-furanone ; CCRIS 8967 ; Ceoxx ; HSDB 7262 ; MK 0966 ; MK 966 ; MK0966 ; UNII-0QTW8Z7MCR ; Vioxx .?Rofecoxib (CAS NO.162011-90-7) is off-white?to pale yellow crystalline powder. |
| Color: | White to off-white to light yellow powder |
| Usage: | A selective cyclooxygenase-2 (COX-2) inhibitor. Use as an anti-inflammatory |
| Safety Data | |
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