| Identification | |
| Name: | Morphinan-6-one,17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride (1:1), (5a)- |
| Synonyms: | Morphinan-6-one,17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride, (5a)- (9CI);Antaxone;Depade;EN 1639A;NIH 8503;Nalorex;Trexan; |
| CAS: | 16676-29-2 |
| EINECS: | 240-723-0 |
| Molecular Formula: | C20H23NO4.HCl |
| Molecular Weight: | 377.86186 |
| InChI: | InChI=1S/C20H23NO4.ClH/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11;/h3-4,11,15,18,22,24H,1-2,5-10H2;1H/t15-,18+,19+,20-;/m1./s1 |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 274-2760C |
| Density: | 1.47 g/cm3 |
| Water Solubility: | H2O: 50 mg/mL, clear, colorless |
| Solubility: | H2O: 50 mg/mL, clear, colorless |
| Appearance: | white crystalline powder |
| Specification: |
Naltrexone hydrochloride (CAS NO.16676-29-2) also can be called Celupan ; Antaxone ; Trexan ; ReVia ; Nalorex .It is marketed in generic form as its hydrochloride salt, naltrexone hydrochloride, and marketed under the trade names Revia and Depade.In some countries including the United States, an extended-release formulation is marketed under the trade name Vivitrol. Also in the US, Methylnaltrexone Bromide, a closely related drug, is marketed as Relistor, for the treatment of Opioid Induced Constipation.While both naltrexone and naloxone are full antagonists and will treat an opioid overdose, naltrexone is longer-acting than naloxone, making naloxone a better emergency antidote. |
| Biological Activity: | Opioid antagonist. |
| Storage Temperature: | 2-8°C |
| Usage: | Nonselective opioid receptor antagonist; congener of naloxone |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
|
 |
|
