| Identification |
| Name: | 3-Pyrrolidinol,5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-, (3R,5R)- |
| Synonyms: | 3-Pyrrolidinol,5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-, (3R-trans)- |
| CAS: | 167144-79-8 |
| Molecular Formula: | C22H29 N O3 |
| Molecular Weight: | 391.93 |
| InChI: | InChI=1/C22H29NO3.ClH/c1-23-16-20(24)15-19(23)12-13-26-22-9-4-3-7-18(22)11-10-17-6-5-8-21(14-17)25-2;/h3-9,14,19-20,24H,10-13,15-16H2,1-2H3;1H/t19-,20-;/m1./s1 |
| Molecular Structure: |
![(C22H29NO3) 3-Pyrrolidinol,5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-, (3R-trans)-](https://img1.guidechem.com/chem/e/dict/57/167144-79-8.jpg) |
| Properties |
| Flash Point: | 246.8°C |
| Boiling Point: | 484.5°Cat760mmHg |
| Density: | g/cm3 |
| Biological Activity: | Potent, selective 5-HT 2 receptor antagonist; displays some selectivity for 5-HT 2A receptors (K i = 1.6 nM). IC 50 values are 2.2, 310, 2400, 3700, > 5000 and > 5000 nM for 5-HT 2 , a 1 -adrenergic, D 2 dopamine, 5-HT 1 , 5-HT 3 and b-adrenergic receptors respectively. Inhibits 5-HT-induced platelet aggregation and pressor responses in vivo . |
| Flash Point: | 246.8°C |
| Safety Data |
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