| Identification | |
| Name: | 1,3-Dioxolo[4,5-g]phthalazine-6(5H)-carboxamide,8-(4-aminophenyl)-5-methyl-N-propyl- |
| Synonyms: | SYM 2206 |
| CAS: | 173952-44-8 |
| Molecular Formula: | C20H22 N4 O3 |
| Molecular Weight: | 366.41 |
| InChI: | InChI=1/C20H22N4O3/c1-3-8-22-20(25)24-12(2)15-9-17-18(27-11-26-17)10-16(15)19(23-24)13-4-6-14(21)7-5-13/h4-7,9-10,12H,3,8,11,21H2,1-2H3,(H,22,25) |
| Molecular Structure: |  |
| Properties | |
| Flash Point: | °C |
| Boiling Point: | °Cat760mmHg |
| Density: | 1.37g/cm3 |
| Refractive index: | 1.673 |
| Biological Activity: | Novel, potent, non-competitive AMPA receptor antagonist (IC 50 = 2.8 μ M ). Acts allosterically at the same regulatory site as GYKI 52466 and 53655 and other benzodiazepines but does not bind to the central diazepine binding site. Selective for AMPA relative to kainate receptor sub-types. Similar potency to GYKI 53655. Anticonvulsant in vivo . |
| Flash Point: | °C |
| Safety Data | |
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