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Benzeneacetic acid, a-amino-a-cyclopropyl-4-phosphono- (183364-82-1)

Identification
Name:Benzeneacetic acid, a-amino-a-cyclopropyl-4-phosphono-
Synonyms:CPPG;a-Cyclopropyl-4-phosphonophenylglycine
CAS:183364-82-1
Molecular Formula: C11H14 N O5 P
Molecular Weight: 271.21
Molecular Structure: (C11H14NO5P) CPPG;a-Cyclopropyl-4-phosphonophenylglycine
Properties
Biological Activity: Potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC 50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (K b = 0.65 ± 0.07 nM). Also available as part of the Group III mGlu Receptor Tocriset™ .
Safety Data