| Identification |
| Name: | Piperazine,1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methyl- |
| Synonyms: | Dibenzo[b,f]thiepin,piperazine deriv.; Methiotepin; Methiothepin; Methiothepine; Metitepine; Ro8-6837 |
| CAS: | 20229-30-5 |
| Molecular Formula: | C20H24 N2 S2 |
| Molecular Weight: | 472.62 |
| InChI: | InChI=1/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3/p+2/t18-/m0/s1 |
| Molecular Structure: |
![(C20H24N2S2) Dibenzo[b,f]thiepin,piperazine deriv.; Methiotepin; Methiothepin; Methiothepine; Metitepine; Ro8-683...](https://img1.guidechem.com/chem/e/dict/181/20229-30-5.jpg) |
| Properties |
| Flash Point: | 233.8°C |
| Boiling Point: | 462.9°Cat760mmHg |
| Density: | 1.25g/cm3 |
| Biological Activity: | Potent 5-HT 2 antagonist, also active as 5-HT 1 antagonist. Differentiates 5-HT 1D sub-types. Also displays affinity for rodent 5-HT 5B , 5-HT 5A , 5-HT 7 and 5-HT 6 receptors (pK 1 values are 6.6, 7.0, 8.4 and 8.7 respectively). |
| Flash Point: | 233.8°C |
| Color: | white |
| Safety Data |
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