| Identification | |
| Name: | Darunavir |
| Synonyms: | Carbamicacid,[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-,(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester (9CI);Carbamic acid,[3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-,hexahydrofuro[2,3-b]furan-3-yl ester, [3R-[3a(1S*,2R*),3ab,6ab]]-;Prezista;TMC 114;TMC 114 (inhibitor);UIC 94017; |
| CAS: | 206361-99-1 |
| Molecular Formula: | C27H37N3O7S |
| Molecular Weight: | 547.66 |
| InChI: | InChI=1/C27H37N3O7S/c1-18(2)15-30(38(33,34)21-10-8-20(28)9-11-21)16-24(31)23(14-19-6-4-3-5-7-19)29-27(32)37-25-17-36-26-22(25)12-13-35-26/h3-11,18,22-26,31H,12-17,28H2,1-2H3,(H,29,32)/t22-,23-,24+,25-,26+/m0/s1 |
| Molecular Structure: | amino]-2-hydroxy-1-(phenylmethyl)p...](https://img.guidechem.com/casimg/206361-99-1.gif) |
| Properties | |
| Density: | 1.34g/cm3 |
| Refractive index: | 1.62 |
| Solubility: | In water, 8.7 mg/L at 25 deg C (est) |
| Appearance: | White Amorphous Solid |
| Specification: |
Darunavir , with CAS number of 206361-99-1, can be called Carbamicacid,[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-,(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester (9CI) ; Carbamic acid,[3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-,hexahydrofuro[2,3-b]furan-3-yl ester, [3R-[3a(1S*,2R*),3ab,6ab]]- . It is a white amorphous solid, used as an second generation HIV-1-protease inhibitor; structurally similar to amprenavir. |
| Color: | White, amorphous solid |
| Usage: | Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral |
| Safety Data | |
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