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Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl- (24219-97-4)

Identification
Name:Dibenzo[c,f]pyrazino[1,2-a]azepine,1,2,3,4,10,14b-hexahydro-2-methyl-
CAS:24219-97-4
EINECS: 246-088-6
Molecular Formula: C18H20 N2
Molecular Weight: 264.40
InChI: InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3
Molecular Structure: (C18H20N2) (?à)-Mianserin; Mianserin;Mianserine
Properties
Transport:3249
Flash Point: 186.1°C
Boiling Point: 411.3°Cat760mmHg
Density:1.18g/cm3
Specification:

 Mianserine (CAS NO.24219-97-4) is also called 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine ; BRN 0755346 ; HSDB 7182 ; Mianserin ; Mianserina ; Mianserina [INN-Spanish] ; Mianserine [INN-French] ; Mianserinum ; Mianserinum [INN-Latin] ; Mianseryna ; Mianseryna [Polish] ; UNII-250PJI13LM ; Dibenzo(c,f)pyrazino(1,2-a)azepine, 1,2,3,4,10,14b-hexahydro-2-methyl- . Mianserine (Bolvidon, Norval, Tolvon) is a psychoactive drug of the tetracyclic antidepressant (TeCA) chemical class which is classified as a noradrenergic and specific serotonergic antidepressant (NaSSA) and has antidepressant, anxiolytic, hypnotic, antiemetic, orexigenic, and antihistamine effects. It was previously available internationally, however in most markets it has been phased out in favor of its analogue and successor mirtazapine (Remeron). An interesting scientific fact is that upon administration, Mianserine has been shown to increase the life span of the nematode Caenorhabditis elegans by as much as 30% via dietary restriction caused by modulation of serotonin receptors in the species. But if the animals are kept in a high-food environment mianserin increases obesity and actually decreases the lifespan.

Packinggroup: III
Flash Point: 186.1°C
Usage:

 Mianserine (CAS NO.24219-97-4) is used as serotonin receptor antagonist.

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