| Identification |
| Name: | 1,2,4-Oxadiazole,5-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]- |
| Synonyms: | SEW 2871 |
| CAS: | 256414-75-2 |
| Molecular Formula: | C20H10 F6 N2 O S |
| Molecular Weight: | 440.36 |
| InChI: | InChI=1/C20H10F6N2OS/c21-19(22,23)13-8-4-7-12(9-13)17-27-18(29-28-17)15-10-14(11-5-2-1-3-6-11)16(30-15)20(24,25)26/h1-10H |
| Molecular Structure: |
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| Properties |
| Transport: | UN 2811 6.1/PG 3 |
| Melting Point: | 94.5-95.3 °C
|
| Flash Point: | 250.3°C |
| Boiling Point: | 490.3°Cat760mmHg |
| Density: | 1.415g/cm3 |
| Refractive index: | 1.535 |
| Appearance: | white solid |
| Biological Activity: | Novel, potent and selective sphingosine-1-phosphate 1 (S1P 1 ) receptor agonist. Activates S1P 1 receptor with an EC 50 of 13 nM, but does not activate S1P 2 , S1P 3 , S1P 4 or S1P 5 receptors at concentrations up to 10 μ M. Cell-permeable and active in vivo . |
| Flash Point: | 250.3°C |
| Storage Temperature: | 2-8°C |
| Color: | white |
| Safety Data |
| Hazard Symbols |
T: Toxic
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