| Identification | |
| Name: | LE 300 |
| Synonyms: | LE 300;7-METHYL-6,7,8,9,14,15-HEXAHYDRO-5H-BENZ[D]INDOLO[2,3-G]AZECINE;6,7,8,9,14,15-HEXAHYDRO-7-METHYL-5H-INDOLO[3,2-F][3]BENZAZECINE;6,7,8,9,14,15-Hexahydro-7-methyl-5H-indolo[3,2-f]benzazecine |
| CAS: | 274694-98-3 |
| Molecular Formula: | C20H22N2 |
| Molecular Weight: | 290.4 |
| InChI: | InChI=1/C20H22N2/c1-22-12-10-15-6-2-3-7-16(15)14-20-18(11-13-22)17-8-4-5-9-19(17)21-20/h2-9,21H,10-14H2,1H3 |
| Molecular Structure: | ![(C20H22N2) LE 300;7-METHYL-6,7,8,9,14,15-HEXAHYDRO-5H-BENZ[D]INDOLO[2,3-G]AZECINE;6,7,8,9,14,15-HEXAHYDRO-7-MET...](https://img.guidechem.com/structure/274694-98-3.gif) |
| Properties | |
| Flash Point: | 234.4°C |
| Boiling Point: | 464°C at 760 mmHg |
| Density: | 1.114g/cm3 |
| Refractive index: | 1.63 |
| Biological Activity: | Potent and selective dopamine D 1 receptor antagonist (K i values are 0.08-1.9 nM and 6-45 nM for D 1 and D 2 receptors respectively). Also displays moderate affinity for the 5-HT 2A receptor (K i = 20 nM). Active in vivo . |
| Flash Point: | 234.4°C |
| Safety Data | |
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