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4H-Dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)- (314-19-2)

Identification
Name:4H-Dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride (1:1), (6aR)-
Synonyms:4H-Dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (6aR)- (9CI);4H-Dibenzo[de,g]quinoline-10,11-diol, 5,6,6a,7-tetrahydro-6-methyl-,hydrochloride, (R)-;6ab-Aporphine-10,11-diol, hydrochloride (8CI);(-)-Apomorphine hydrochloride;Apomorphine hydrochloride;Apomorphinium chloride;NSC 11442;R-(-)-Apomorphinehydrochloride;Uprima;
CAS:314-19-2
EINECS: 206-243-0
Molecular Formula: C17H17 N O2 . Cl H
Molecular Weight: 303.81
InChI: InChI=1/C17H17NO2.ClH/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;/h2-6,13,19-20H,7-9H2,1H3;1H
Molecular Structure: (C17H17NO2.ClH) 4H-Dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, (6aR)- (9CI);4H-D...
Properties
Transport:3249
Melting Point: 195 deg C (decomposes)
Flash Point: 268.8°C
Boiling Point: 473.4°Cat760mmHg
Density:g/cm3
Solubility:Sol in alcohol, acetone, chloroform; slightly sol in water, benzene, ether, petroleum ether
Slightly soluble in hydrochloric acid, ligand; soluble in ethanol, ethyl ether, acetone, benzene, chloroform, alkalies
In water, 1.66X10+4 mg/L at 16 deg C
Specification:

 Apormorphine chloride (CAS NO.314-19-2) is also called (-)-Apomorphiniumhydrochloride ; (r)-id ; (theta)-id ; 11-diol,6-methyl-6a-beta-Noraporphine-1hydrochloride ; 6a-beta-Aporphine-10,11-diol,hydrochloride ; Apomorphinechloride . Apormorphine chloride (CAS NO.314-19-2) is high toxic. It is flammable. It will produce toxic fumes when buring. So the storage environment should be ventilate, low-temperature and dry. Keep Apormorphine chloride (CAS NO.314-19-2) separate from raw materials of food.

Report:

Reported in EPA TSCA Inventory.

Packinggroup: III
Biological Activity: Prototypical dopamine agonist (pK i values are 6.43, 7.08, 7.59, 8.36 and 7.83 for human recombinant D 1 , D 2L , D 3 , D 4 and D 5 receptors respectively). Produces biphasic effects on locomotor activity, and displays anti-Parkinsonian and neuroprotective actions following systemic administration in vivo .
Flash Point: 268.8°C
Color: Hexagonal plates from chloroform+petroleum ether; rods from ether
Safety Data
 

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