| Identification | |
| Name: | Paclitaxel |
| Synonyms: | 7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.; taxal; taxol a |
| CAS: | 33069-62-4 |
| EINECS: | 205-285-7 |
| Molecular Formula: | C47H51NO14 |
| Molecular Weight: | 853.92 |
| InChI: | InChI=1/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35+,36+,37+,38-,40-,45+,46-,47+/m0/s1 |
| Molecular Structure: | ![(C47H51NO14) 7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv.; taxal; taxol a](https://img.guidechem.com/casimg/33069-62-4.gif) |
| Properties | |
| Transport: | 1544 |
| Density: | 1.39g/cm3 |
| Stability: | Stable. Incompatible with strong oxidizing agents. Combustible. |
| Water Solubility: | solubile in methanol: 50 mg/mL, clear, colorless |
| Solubility: | solubile in methanol: 50 mg/mL, clear, colorless |
| Appearance: | White Powder |
| Specification: |
? Paclitaxel (CAS NO.33069-62-4), its Synonyms are 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv ; Taxal ; Taxol A? . |
| Packinggroup: | III |
| Biological Activity: | Antitumor agent; promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis. |
| Color: | white |
| Usage: | An antineoplastic. Used in the study of structure and function of microtubles into tubulin |
| Safety Data | |
| Hazard Symbols |
Xn:Harmful
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