| Identification | |
| Name: | Benzamide,N-[4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]- |
| Synonyms: | N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide; |
| CAS: | 331771-20-1 |
| Molecular Formula: | C29H31N5O4 |
| Molecular Weight: | 513.59 |
| InChI: | InChI=1/C29H31N5O4/c1-36-26-18-24-25(19-27(26)38-15-5-12-34-13-16-37-17-14-34)30-20-31-28(24)32-22-8-10-23(11-9-22)33-29(35)21-6-3-2-4-7-21/h2-4,6-11,18-20H,5,12-17H2,1H3,(H,33,35)(H,30,31,32) |
| Molecular Structure: | ![(C29H31N5O4) N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide;](https://img1.guidechem.com/chem/e/dict/158/331771-20-1.jpg) |
| Properties | |
| Flash Point: | 340.661oC |
| Boiling Point: | 639.671oC at 760 mmHg |
| Density: | 1.282 g/cm3 |
| Refractive index: | 1.664 |
| Appearance: | Pale yellow solid |
| Flash Point: | 340.661oC |
| Usage: |
N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide (CAS NO.331771-20-1) is a potent and selective inhibitor of Aurora B kinase. Cells treated with ZM-447439 progress through interphase, enter mitosis and assemble bipolar spindles but chromosome alignment, segregation and cytokinesis all fail. |
| Safety Data | |
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