| Identification |
| Name: | 1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-, (1Z)- |
| Synonyms: | 1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-, (Z)-;(Z)-5-Fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid;Aflodac;Arthrocine;Artribid;Clinoril;Clisundac;Imbaral;MK 231;Mobilin;Reumofil;Reumyl;Sudac; |
| CAS: | 38194-50-2 |
| EINECS: | 253-819-2 |
| Molecular Formula: | C20H17FO3S |
| Molecular Weight: | 356.41 |
| InChI: | InChI=1/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9- |
| Molecular Structure: |
![(C20H17FO3S) 1H-Indene-3-aceticacid, 5-fluoro-2-methyl-1-[[4-(methylsulfinyl)phenyl]methylene]-, (Z)-;(Z)-5-Fluor...](https://img.guidechem.com/casimg/38194-50-2.gif) |
| Properties |
| Transport: | 3249 |
| Density: | 1.38 g/cm3 |
| Stability: | Stable at normal temperatures and pressures. |
| Refractive index: | 1.672 |
| Water Solubility: | Soluble in DMSO or aqueous bases. |
| Solubility: | Soluble in DMSO or aqueous bases. |
| Appearance: | Yellow solid. |
| Packinggroup: | III |
| Biological Activity: | Prodrug. Metabolizes to sulindac sulfide, a cyclooxgenase inhibitor that represses ras signaling, and sulindac sulfone, an antitumor agent, following oral administration in vivo . Widely used anti-inflammatory agent. |
| Storage Temperature: | Keep tightly closed. |
| Usage: | A non-steroidal anti-inflammatory agent. An anti-inflammatory |
| Safety Data |
| Hazard Symbols |
Xn:Harmful
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