Home >> Chemicals Listing >> hot product list by 2  

2-Amino-4-hydroxy-6-methylpyrimidine (3977-29-5)

Identification
Name:2-Amino-4-hydroxy-6-methylpyrimidine
Synonyms:2-Amino-6-methyl-4-pyrimidinol; 2-amino-4-methyl-6(1h)-pyrimidinon
CAS:3977-29-5
EINECS: 223-612-1
Molecular Formula: C5H7N3O
Molecular Weight: 125.13
InChI: InChI=1/C5H7N3O/c1-3-2-4(9)8-5(6)7-3/h2H,1H3,(H3,6,7,8,9)
Molecular Structure: (C5H7N3O) 2-Amino-6-methyl-4-pyrimidinol; 2-amino-4-methyl-6(1h)-pyrimidinon
Properties
Density:1.44 g/cm3
Stability:Stable under normal temperatures and pressures.
Refractive index:1.651
Appearance:White Powder
Specification:

The 2-Amino-4-hydroxy-6-methylpyrimidine with the cas number 3977-29-5. It is also called (1)2-Amino-6-methylpyrimidin-4-ol ; (2)4-Methylisocytosine ; (3)6-Methylisocytosine ; (4)4(1H)-Pyrimidinone, 2-amino-6-methyl- . It belongs to the following product categories: (1)Pyrimidine; (2)Fluorobenzene; (3)Amines; (4)Pyrimidines

Properties of 2-Amino-4,6-Dimethylpyrimidine : (1)ACD/LogP: 0.70 ; (2)# of Rule of 5 Violations: 0 ; (3)ACD/LogD (pH 5.5): 0.64 ; (4)ACD/LogD (pH 7.4): 0.7 ; (5)ACD/BCF (pH 5.5): 1.74 ; (6)ACD/BCF (pH 7.4): 2 ; (7)ACD/KOC (pH 5.5): 49.7 ; (8)ACD/KOC (pH 7.4): 57.15 ; (9)#H bond acceptors: 3 ; (10)#H bond donors: 2 ; (11)#Freely Rotating Bonds: 0 ; (12)Polar Surface Area: 29.02 Å2 ; (13)Index of Refraction: 1.569 ; (14)Molar Refractivity: 36.32 cm3 ; (15)Molar Volume: 110.7 cm3 ; (16)Polarizability: 14.39 ×10-24cm3 ; (17)Surface Tension: 51.5 dyne/cm ; (18)Density: 1.112 g/cm3 ; (19)Flash Point: 156.7 °C ; (20)Enthalpy of Vaporization: 53.37 kJ/mol ; (21)Boiling Point: 294 °C at 760 mmHg ; (22)Vapour Pressure: 0.00166 mmHg at 25°C

The 2-Amino-4-hydroxy-6-methylpyrimidine seems like white powder. It is quite irritating to eyes, respiratory system and skin. When you are using this chemical, please wear suitable gloves and eye/face protection to avoid contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

The 2-amino-6-methyl-5-nitro-3H-pyrimidin-4-one can be obatined from 2-Amino-4-hydroxy-6-methylpyrimidine in conc. HNO3, conc. H2SO4 as reagents, with ambient temperature for 3 hour(s). Yield is 48 % .


The 2-Amino-4-hydroxy-6-methylpyrimidine can also be obtained from 2-methoxy-6-methyl-3H-pyrimidin-4-one with heating for 24 hour(s). Yield is 52 % .

You can still convert the following datas into molecular structure :
1. SMILES: O=C/1/N=C(/N)N\C(=C\1)C
2. InChI: InChI=1/C5H7N3O/c1-3-2-4(9)8-5(6)7-3/h2H,1H3,(H3,6,7,8,9)

Toxic information of 2-Amino-4-hydroxy-6-methylpyrimidine can be showed as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LDLo oral 11gm/kg (11000mg/kg) BEHAVIORAL: TREMOR

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 National Technical Information Service. Vol. OTS0540498,

Storage Temperature: Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Safety Data
Hazard Symbols Xi:Irritant
 

Other Product