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capsaicin (404-86-4)

Identification
Name:capsaicin
Synonyms:Capsaicine; 8-Methyl-N-vanillyl-6-nonenamide;
CAS:404-86-4
EINECS: 206-969-8
Molecular Formula: C18H27NO3
Molecular Weight: 305.42
InChI: InChI=1/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
Molecular Structure: (C18H27NO3) Capsaicine; 8-Methyl-N-vanillyl-6-nonenamide;
Properties
Transport:UN 2811
Flash Point: 263.1oC
Boiling Point: 511.5oCat760mmHg
Density:1.041g/cm3
Stability:Stable. Incompatible with strong oxidizing agents.
Water Solubility:insoluble
Solubility:practically insoluble in cold water
Appearance:white crystalline powder
Specification:
Off-White Crystalline Solid
usageEng:A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.
Safety Statements:22-26-28-36/39-45-36/37/39
22:Do not breathe dust
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36/39:Wear suitable protective clothing and eye/face protection
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
Packinggroup: II
Biological Activity: Prototypic vanilloid receptor agonist (pEC 50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a subset of primary afferent sensory neurons, with subsequent antinociceptive and anti-inflammatory effects. Reversibly inhibits aggregation of platelets. Also available as part of the Vanilloid TRPV1 Receptor Tocriset? .
Flash Point: 263.1oC
Color: Pure dark red solid
Monoclinic rectangular plates and scales from petroleum ether
Usage:

A representative lot is a 5:1 E:Z mixture. It is used as a tool in neurobiological research. Prototype vanilloid receptor agonist. Topical analgesic.

Safety Data
Hazard Symbols T:Toxic