| Identification |
| Name: | 2-[(2-oxonaphthalen-1-ylidene)methylamino]-N-[(1R)-1-phenylethyl]benzamide |
| Synonyms: | 2-[(2-HYDROXYNAPHTHALEN-1-YLMETHYLENE)AMINO]-N-(1-PHENETHYL)BENZAMIDE;SIRTINOL;SIR TWO INHIBITOR NAPHTHOL |
| CAS: | 410536-97-9 |
| Molecular Formula: | C26H22N2O2 |
| Molecular Weight: | 394.4651 |
| InChI: | InChI=1/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18,27H,1H3,(H,28,30)/t18-/m1/s1 |
| Molecular Structure: |
![(C26H22N2O2) 2-[(2-HYDROXYNAPHTHALEN-1-YLMETHYLENE)AMINO]-N-(1-PHENETHYL)BENZAMIDE;SIRTINOL;SIR TWO INHIBITOR NAP...](https://img.guidechem.com/cas/gif/410536-97-9.gif) |
| Properties |
| Flash Point: | 211.4°C |
| Boiling Point: | 650°Cat760mmHg |
| Density: | 1.276g/cm3 |
| Refractive index: | 1.711 |
| Biological Activity: | Cell-permeable, selective sirtuin deacetylase inhibitor (IC 50 values are 38, 68 and 131 μ M at SIRT2, Sir2p and SIRT1 respectively) that has no effect on HDAC1 activity. Significantly decreases growth and viability of PCa and HEK293T cells in vitro . |
| Flash Point: | 211.4°C |
| Storage Temperature: | −20°C |
| Safety Data |
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