(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE (440100-64-1)

Identification
Name:	(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE
Synonyms:	(2S)-1-[[[4-METHYL-1-(2-PYRIMIDINYL)-4-PIPERIDINYL]AMINO]ACETYL]-2-PYRROLIDINECARBONITRILE;K 579
CAS:	440100-64-1
Molecular Formula:	C17H24N6O
Molecular Weight:	0
Molecular Structure:
Properties
Biological Activity:	Dipeptidyl peptidase IV inhibitor. Inhibits rat, canine, human and monkey enzymes with IC 50 values of 3, 5, 8, and 8 nM respectively. Long-acting hypoglycemic agent; attenuates glucose excursion following glucose loading in Zucker fatty rats.
Safety Data

Other Product

2-Pyrrolidinecarbonitrile, 1-[[[(4-fluorophenyl)methyl]amino]acetyl]-,(2S)-
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[(1-formyl-4-methyl-4-piperidinyl)amino]acetyl]-, (2S,4S)-,(2E)-2-butenedioate (1:1)
2-Pyrrolidinecarbonitrile,1-[[[1-(ethylsulfonyl)-4-methyl-4-piperidinyl]amino]acetyl]-4-fluoro-,(2S,4S)-, (2E)-2-butenedioate (1:1)
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[4-methyl-1-(methylsulfonyl)-4-piperidinyl]amino]acetyl]-,(2S,4R)-, (2E)-2-butenedioate (1:1)
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[1-(methylsulfonyl)-4-piperidinyl]amino]acetyl]-, (2S,4S)-
2-Pyrrolidinecarbonitrile,1-[[[2-(2,6-dimethyl-1-piperidinyl)-1,1-dimethylethyl]amino]acetyl]-4-fluoro-, (2S,4S)-
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[4-methyl-1-(methylsulfonyl)-4-piperidinyl]amino]acetyl]-
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[(1-formyl-4-methyl-4-piperidinyl)amino]acetyl]-
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[1-(methylsulfonyl)-4-piperidinyl]amino]acetyl]-, (2S,4S)-,(2E)-2-butenedioate (1:1)
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[1-methyl-1-(2-pyridinyl)ethyl]amino]acetyl]-, (2S,4S)-
2-Pyrrolidinecarbonitrile,1-[[[(1R,4S)-4-[(2-pyridinylthio)methyl]-2-cyclopenten-1-yl]amino]acetyl]-, (2S)-
2-Pyrrolidinecarbonitrile,1-[[[(1R,3S)-3-[[(2-fluoro-4-nitrophenyl)amino]methyl]cyclopentyl]amino]acetyl]-, (2S)-
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[1-methyl-1-(3-thienyl)ethyl]amino]acetyl]-, (2S,4S)-
2-Pyrrolidinecarbonitrile,1-[[[(1S,3R)-3-[[(4-fluorophenyl)thio]methyl]cyclopentyl]amino]acetyl]-,(2S)-
2-Pyrrolidinecarbonitrile,1-acetyl-, (2S)-
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[4-methyl-1-(methylsulfonyl)-4-piperidinyl]amino]acetyl]-,(2R,4S)-, (2E)-2-butenedioate (1:1)
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[4-methyl-1-(methylsulfonyl)-4-piperidinyl]amino]acetyl]-,(2R,4R)-, (2E)-2-butenedioate (1:1)
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[trans-1-methyl-4-[[(1-methylethylidene)amino]oxy]cyclohexyl]amino]acetyl]-, (2S,4S)-
2-Pyrrolidinecarbonitrile,1-[[[4-[[(4-fluorophenyl)sulfonyl]amino]bicyclo[2.2.2]oct-1-yl]amino]acetyl]-, (2S)-
2-Pyrrolidinecarbonitrile,4-fluoro-1-[[[1-(methylsulfonyl)-4-piperidinyl]amino]acetyl]-