3-Pyridinecarboxamide,N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]- (453562-69-1)

The cas register number of Motesanib is 453562-69-1. It also can be called as N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide and the Systematic name about this chemical is N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide. Classification Code about this chemica lare Angiogenic agent, Antiangiogenesis agent and Antineoplastic Agents. This chemical can be used as a c-KIT protein inhibitor and antineoplastic agent.

Physical properties about Motesanib are: (1)ACD/LogP: 3.88; (2)ACD/LogD (pH 5.5): 4; (3)ACD/LogD (pH 7.4): 4; (4)ACD/BCF (pH 5.5): 457; (5)ACD/BCF (pH 7.4): 947; (6)ACD/KOC (pH 5.5): 2262; (7)ACD/KOC (pH 7.4): 4685; (8)#H bond acceptors: 6; (9)#H bond donors: 3; (10)#Freely Rotating Bonds: 4; (11)Polar Surface Area: 78.94Ų; (12)Index of Refraction: 1.669; (13)Molar Refractivity: 111.34 cm³; (14)Molar Volume: 298.448 cm³; (15)Polarizability: 44.139x10^-24cm³; (16)Surface Tension: 59.321 dyne/cm; (17)Enthalpy of Vaporization: 78.953 kJ/mol.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(c2cccnc2NCc1ccncc1)Nc3ccc4c(c3)NCC4(C)C
(2)InChI: InChI=1/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
(3)InChIKey: RAHBGWKEPAQNFF-UHFFFAOYAA
(4)Std. InChI: InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)
(5)Std. InChIKey: RAHBGWKEPAQNFF-UHFFFAOYSA-N