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Lup-20(29)-ene-3,28-diol,(3b)- (473-98-3)

Identification
Name:Lup-20(29)-ene-3,28-diol,(3b)-
Synonyms:Lup-20(29)-ene-3b,28-diol(8CI); Lup-20(30)-ene-3b,28-diol (6CI); 3aH-Cyclopenta[a]chrysene,lup-20(29)-ene-3,28-diol deriv.; (+)-Betulin; 3,28-Dihydroxy-lupeol; 3b,28-Dihydroxylup-20(29)-ene;Betulin; Betuline; Betulinic alcohol; Betulinol; Betulol; NSC 4644; Trochol
CAS:473-98-3
EINECS: 207-475-5
Molecular Formula: C30H50 O2
Molecular Weight: 442.72 .
InChI: InChI=1/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22?,23?,24-,25?,27-,28+,29+,30+/m0/s1
Molecular Structure: (C30H50O2) Lup-20(29)-ene-3b,28-diol(8CI); Lup-20(30)-ene-3b,28-diol (6CI); 3aH-Cyclopenta[a]chrysene,lup-20(29...
Properties
Transport: OTH
Melting Point: 256 - 257 C
Density:1.017g/cm3
Stability:Stable under recommended storage conditions. Material is air and moisture sensitive.
Refractive index:1.5186
Solubility:Insoluble
Appearance:white crystalline powder
Specification:

?Betulin (473-98-3) , which also can be called for Betuline ; Betulinol ; Trochol ; Betulin derivative ; 3b-Lup-20(29)-ene-3,28-diol? ,?is an abundant naturally occurring triterpene. It is commonly isolated from the bark of birch trees and forms up to 30% of the dry weight of the extractive. Betulin (473-98-3) has been used for herbs' ingredient and? raw materials of health care products.It can be converted to betulinic acid which is biologically more active than betulin itself.Betulinic acid and its synthetic analogues exhibit anti-malarial, anti-inflamatory and anti-HIV activity as well as showing cytotoxicity towards a number of tumour cell lines. Even though betulin derivatives are most widely studied for their anticancer activity, also the anti-HIV effect is quite well characterized and it has been demonstrated that betulins can inhibit HIV entry to T cells by binding to the gp41, an HIV protein needed for the invasion of the virus into the cell.

HS Code: 29181985
Usage:

Exhibits anti-malarial, anti-inflamatory and anti-hiv activity as well as showing cytotoxicity towards a number of tumour cell lines.

Safety Data
Hazard Symbols Xi: Irritant