| Identification |
| Name: | VX-702 |
| Synonyms: | 3-Pyridinecarboxamide, 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-;6-[Carbamoyl(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)nicotinamide |
| CAS: | 479543-46-9 |
| Molecular Formula: | C19H12F4N4O2 |
| Molecular Weight: | 404.322 |
| InChI: | InChI=1/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29) |
| Molecular Structure: |
![(C19H12F4N4O2) 3-Pyridinecarboxamide, 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-;6-[Carba...](https://img.guidechem.com/structure/479543-46-9.gif) |
| Properties |
| Flash Point: | 289.6°C |
| Boiling Point: | 555.2°C at 760 mmHg |
| Density: | 1.503g/cm3 |
| Refractive index: | 1.628 |
| Biological Activity: | Orally active, ATP-competitive inhibitor of p38α MAPK; also inhibits p38β (K D values are 3.7 and 17 nM respectively). |
| Flash Point: | 289.6°C |
| Safety Data |
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