| Identification | |
| Name: | 2H-1,3,2-Oxazaphosphorin-2-amine,N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide |
| Synonyms: | 2H-1,3,2-Oxazaphosphorine,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide (6CI,8CI);(RS)-Cyclophosphamide;2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide;Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester;CB 4564;CY;Clafen;Claphene;Cycloblastin;Cyclophosphamid;Cyclophosphan;Cyclophosphane;Cyclostin;Cytophosphan;Cytoxan;Endoxan;Endoxan R;Endoxan-Asta;Endoxana;Endoxanal;Endoxane;Enduxan;Genoxal;Mitoxan;N,N-Bis(b-chloroethyl)-N',O-trimethylenephosphoricacid ester diamide;Neosar;Neosar (antineoplastic);Procytox;Revimmune;SK 20501;Semdoxan;Sendoxan;Senduxan;Zyklophosphamid; |
| CAS: | 50-18-0 |
| EINECS: | 200-015-4 |
| Molecular Formula: | C7H15Cl2N2O2P |
| Molecular Weight: | 261.09 |
| InChI: | InChI=1/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12) |
| Molecular Structure: | ![(C7H15Cl2N2O2P) 2H-1,3,2-Oxazaphosphorine,2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide (6CI,8CI);(RS)-Cyclophosph...](https://img.guidechem.com/casimg/50-18-0.gif) |
| Properties | |
| Transport: | UN 1851 |
| Density: | 1.33 g/cm3 |
| Stability: | Stable, but light sensitive. Incompatible with oxidizing agents. |
| Solubility: | Soluble. 1-5 g/100 mL at 23 oC |
| Appearance: | white crystalline powder |
| Report: |
NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 182.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 , 1981,p. 165.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 26 , 1981,p. 165.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 , 1975,p. 135.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 9 , 1975,p. 135.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Studies (ipr); Clear Evidence: mouse, rat RRCRBU ?? Recent Results in Cancer Research. 52 (1975),1. . EPA Genetic Toxicology Program. |
| Packinggroup: | III |
| Color: | LIQUEFIES ON LOSS OF ITS WATER OF CRYSTALLIZATION Crystalline solid |
| Safety Data | |
| Hazard Symbols | |
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