| Identification | |
| Name: | Fluorouracil (5-Fluorouracil) |
| Synonyms: | Ro-2-9757;Phtoruracil;Ulup;2,4(1H,3H)-Pyrimidinedione,5-fluoro-;Phthoruracil;Uracil, 5-fluoro-;5-Fluoro-2,4(1H, 3H)-pyrimidinedione;2,4 (1H, 3H)-Pyrimidinedione, 5-fluoro-;5-Fluoro-2,4(1H,3H)-pyrimidinedione;Fluoroplex;5-Fluoracyl;Efudex;Effluderm (free base);U 8953;Adrucil;Efurix;5-Ftouracyl;2,4(1H,3H)-pyrimidinedione, 5-fluoro-;5-Fluoropyrimidine-2,4-dione;U-8953;Arumel;Kecimeton;Fluoroblastin;2,4-Dioxo-5-fluoropryimidine;Fluro Uracil;Uracil, 5-fluoro- (VAN 8CI);Fluracil;Efudix;Ro 2-9757;5-fluoro-1H-pyrimidine-2,4-dione;5-FU (TN);Carzonal;Fluracilum;5-FU;5FU;5-Fluoro-2,4-pyrimidinedione;Fluril;FU;Fluri;Fluorouracil (JP14/USP);Adrucil (TN);Queroplex;Timazin;Fludrocortisone;5-FLUORACIL (GERMAN);5-FLUORO-2,4(1H,3H)-PYRIMIDINEDI-ONE;5-FLUORPROPYRIMIDINE-2,4-DIONE;5-FLUORO-2,4-PYRIMI-DINEDIONE;5-FLUORURACIL (GERMAN);NSC-19893;5-Fluoro Uracil;5-Fluoropyrimidine;Carmofur 5-Fluoro Uracil;5-Fluorouracl;5-Fluorouracilum; |
| CAS: | 51-21-8 |
| EINECS: | 200-085-6 |
| Molecular Formula: | C4H3FN2O2 |
| Molecular Weight: | 130.0772 |
| InChI: | InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9) |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 2811 6.1/PG 3 |
| Density: | 1.53 g/cm3 |
| Stability: | Stable. Light sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases. |
| Refractive index: | 1.542 |
| Solubility: | insoluble in water |
| Appearance: | white to nearly white crystalline powder |
| Specification: |
?Fluorouracil , its cas register number is 51-21-8. It also can be called?2,4(1H,3H)-Pyrimidinedione, 5-fluoro- ; 2,4-Dioxo-5-fluoropyrimidine ; 5-FU ; 5-Faracil ; 5-Fluor-2,4(1H,3H)-pyrimidindion ; 5-Fluor-2,4-dihydroxypyrimidin .It is a?white to nearly white crystalline powder and?insoluble in water. |
| Packinggroup: | III |
| HS Code: | 29335995 |
| Biological Activity: | Anticancer agent. Metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate reductase causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively. |
| Storage Temperature: | Store at 0-5 |
| Sensitive: | Air Sensitive |
| Color: | white |
| Usage: | A potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis |
| Safety Data | |
| Hazard Symbols |
Xn:Harmful
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