| Identification | |
| Name: | Atropine sulfate |
| Synonyms: | Atropen;Atropisol;1-.alpha.-H,5-.alpha.-H-Tropan-3-.alpha.-ol (.+-.)-tropate (ester), sulfate (2:1) salt;Atropinsal;Benzeneacetic acid,R-(hydroxymethyl)- (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3- yl ester,compounds,sulfate (2:1) (salt);1.alpha.H, 5.alpha.H-Tropan-3.alpha.-ol (.+-.)-tropate (ester), sulfate (2:1) (salt);Eyesule;Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, sulfate (2:1) (salt);Sulfate datropine [French];component of Enuretrol;Tropintran;component of Antrocol;Benzeneacetic acid, .alpha.- (hydroxymethyl)- 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester endo-(.+-.)-, sulfate (2:1) (salt);Atropette;Sulfatropinol;Ichtho-bellol;Atropine sulfate (VAN);Ryuato;component of Motofen;component of Isopto Atropine;1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester), sulfate (2:1) (salt) (8CI);Atropin siran;Atropine sulfate anhydrous; |
| CAS: | 55-48-1 |
| EINECS: | 200-235-0 |
| Molecular Formula: | 2(C17H23NO3).H2SO4 |
| Molecular Weight: | 676.82 |
| InChI: | InChI=1/2C17H23NO3.H2O4S/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4) |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 1544 |
| Solubility: | 1 g in: ... 2 mL alcohol, 25 mL ether, 27 mL glycerol, 1 mL chloroform; also sol in benzene, in dil acids Very soluble in ethanol; slightly soluble in chloroform; insoluble in ethyl ether In water, 2,200 mg/l @ 25 deg C |
| Appearance: | White crystalline powder |
| Specification: |
?Atropine sulfate anhydrous (CAS NO.55-48-1) is also named as 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester), sulfate (2:1) salt ; AI3-14072 ; Atropen ; Atropette ; Atropin siran ; Atropin siran [Czech] ; Atropine sulfate ; Atropine sulfate (VAN) ; Atropine sulphate ; Atropine sulphate (VAN) ; Atropine, sulfate (2:1) ; Atropinium sulfate ; Atropisol ; Corbella ; DL-Tropanyl 2-hydroxy-1-phenylpropionate sulfate ; Davurtrop ;?Eyesule ; Ichtho-bellol ; Lio-atropin ; MBK ; NSC 26671 ; Ryuato ; Sulfate d'atropine ; Sulfate d'atropine [French] ; Sulfatropinol ; Tropintran ; UNII-03J5ZE7KA5?.?Atropine sulfate anhydrous (CAS NO.55-48-1) is a tropane alkaloid extracted from deadly nightshade , jimsonweed , mandrake and other plants of the family Solanaceae. It serves as a drug with a wide variety of effects and is a competitive antagonist for the muscarinic acetylcholine receptor. And, it is a core medicine in the World Health Organization's "Essential Drugs List", which is a list of minimum medical needs for a basic health care system. Being potentially deadly, it derives its name from Atropos, one of the three Fates who, according to Greek mythology, chose how a person was to die. Atropine is a racemic mixture of D-hyoscyamine and L-hyoscyamine, with most of its physiological effects due to L-hyoscyamine. Its pharmacological effects are due to binding to muscarinic acetylcholine receptors. It is an antimuscarinic agent. |
| Color: | Long, orthorhombic prisms from acetone Rhombic needles (dilute ethyl alcohol) White crystals or powder |
| Safety Data | |
| Hazard Symbols |
T+: Very toxic
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