Acetamide,N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]- (554-57-4)

The Methazolamide with cas registry number of 554-57-4 is also called Neptazane. Its IUPAC name is called N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide. It also has the EINECS registry number which is 209-066-7. This chemical is a kind of a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.

The physical properties about this chemical are: (1)ACD/LogP: 0.13; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.13; (4)ACD/LogD (pH 7.4): -0.21; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 27.68; (8)ACD/KOC (pH 7.4): 12.81; (9)#H bond acceptors: 7; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Index of Refraction: 1.737; (13)Molar Refractivity: 53.06 cm³; (14)Molar Volume: 131.9 cm³; (15)Surface Tension: 80 dyne/cm; (16)Density: 1.79 g/cm³; (17)Flash Point: 196.9 °C; (18)Enthalpy of Vaporization: 65.31 kJ/mol; (19)Boiling Point: 402 °C at 760 mmHg; (20)Vapour Pressure: 1.13E-06 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful by inhalation, in contact with skin and if swallowed. It has the limited evidence of a carcinogenic effect. Therefore, when using it, wear suitable protective clothing. And do not breathe dust.

You can still convert the following datas into molecular structure:
(1)InChI: InChI=1/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+;
(2)Smiles: c1(\sc(S(N)(=O)=O)nn1C)=N\C(C)=O

The toxicity data is as follows: