5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]- (56990-57-9)

Identification
Name:	5-Quinolinesulfonicacid, 8-hydroxy-7-[2-(6-sulfo-2-naphthalenyl)diazenyl]-
Synonyms:	5-Quinolinesulfonicacid, 8-hydroxy-7-[(6-sulfo-2-naphthalenyl)azo]- (9CI); 5-Quinolinesulfonicacid, 8-hydroxy-7-[(6-sulfo-2-naphthyl)azo]- (7CI); NSC 87877
CAS:	56990-57-9
Molecular Formula:	C19H13 N3 O7 S2
Molecular Weight:	0
InChI:	InChI=1/C19H13N3O7S2/c23-19-16(10-17(31(27,28)29)15-2-1-7-20-18(15)19)22-21-13-5-3-12-9-14(30(24,25)26)6-4-11(12)8-13/h1-10,21H,(H,24,25,26)(H,27,28,29)/b22-16+
Molecular Structure:
Properties
Flash Point:	°C
Boiling Point:	°Cat760mmHg
Density:	1.69g/cm³
Refractive index:	1.757
Biological Activity:	Potent inhibitor of shp2 and shp1 protein tyrosine phosphatases (PTP) (IC 50 values are 0.318, 0.355, 1.691, 7.745, 65.617, 84.473 and 150.930 μ M for shp2, shp1, PTP1B, HePTP, DEP1, CD45 and LAR respectively). Inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
Flash Point:	°C
Safety Data