| Identification | ||
| Name: | Progesterone | |
| Synonyms: | 3,20-pregnene-4; 4-pregnene-3,20-dione; beta-progesterone; corlutin; corlutina; corluvite; corporin; corpus luteum hormone; delta4-pregnene-3,20-dione; delta(sup4)-pregnene-3,20-dione; flavolutan; fologenon; gestone; gestormone; glanducorpin; hormoflaveine; hormoluton; lipolutin; lucorteum sol; luteal hormone; Lutein; luteinique; luteodyn; luteogan; luteohormone; luteol; luteosan; luteostab; luteovis; Lutex; lutidon; lutocyclin; lutocyclin m; lutocylin; lutocylol; lutoform; lutogyl; lutren; lutromone; piaponon; pranone; Pregn-4-ene-3,20-dione; pregnendione; pregnenedione; primolut; progekan; progesterol; progesteronum; progestin; progestone; prolidon; (S)-Pregn-4-en-3,20-dione; synovex s; syntolutan; | |
| CAS: | 57-83-0 | |
| EINECS: | 200-350-6 | |
| Molecular Formula: | C21H30O2 | |
| Molecular Weight: | 314.47 | |
| InChI: | InChI=1/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1 | |
| Molecular Structure: |  |
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| Properties | ||
| Density: | 1.08g/cm3 | |
| Stability: | Stable. Incompatible with strong oxidizing agents. | |
| Alpha: | 186 o (C=1, ETHANOL) | |
| Water Solubility: | <0.1 g/100 mL at 19 ºC | |
| Solubility: | <0.1 g/100 mL at 19 oC | |
| Appearance: | Crystalline Powder | |
| Specification: |
?Progesterone (CAS NO.57-83-0) is also called Progestin ; Lutren ; Lutein ; Flavolutan ; Corporin ; Luteal hormone ; 4-Pregnene-3,20-dione . | |
| Report: |
NTP 10th Report on Carcinogens. IARC Cancer Review: Animal Limited Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 21 ,1979,p. 491.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 6 ,1974,p. 135.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.
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| Biological Activity: | Endogenous progesterone receptor (PR) agonist (EC 50 = 0.5 nM). | |
| Storage Temperature: | Store in a cool, dry place. Store in a tightly closed container. Hormones and antibiotics room. | |
| Color: | White crystalline powder Exists in two crystalline forms | |
| Usage: | Sterid hormone produced by the corpus luteum. Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer | |
| Safety Data | ||
| Hazard Symbols |
Xn:Harmful
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