| Identification | |
| Name: | Cyclosporin B (9CI) |
| Synonyms: | CyclosporinA, 7-L-alanine-;Antibiotic S 7481F2;Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-alanyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]; |
| CAS: | 63775-95-1 |
| Molecular Formula: | C61H109N11O12 |
| Molecular Weight: | 1188.5847 |
| InChI: | InChI=1/C61H109N11O12/c1-25-26-27-39(14)51(74)50-55(78)64-41(16)56(79)66(18)32-47(73)67(19)43(28-33(2)3)54(77)65-48(37(10)11)60(83)68(20)44(29-34(4)5)53(76)62-40(15)52(75)63-42(17)57(80)69(21)45(30-35(6)7)58(81)70(22)46(31-36(8)9)59(82)71(23)49(38(12)13)61(84)72(50)24/h25-26,33-46,48-51,74H,27-32H2,1-24H3,(H,62,76)(H,63,75)(H,64,78)(H,65,77)/b26-25+/t39?,40-,41+,42+,43+,44+,45+,46+,48+,49+,50-,51+/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Melting Point: | 149-152 oC |
| Density: | 1.019 g/cm3 |
| Refractive index: | 1.468 |
| Appearance: | Amorphous white solid |
| Usage: | An immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity. |
| Safety Data | |
 |
|
