Ethanaminium,2,2',2''-[1,2,3-benzenetriyltris(oxy)]tris[N,N,N-triethyl-, iodide (1:3) (65-29-2)

With CAS register number 65-29-2, Gallamine triethiodide is also can be called Tri(beta-diethylaminoethoxy)-1,2,3-benzene triiodoethylate ; Pyrogallol 1,2,3-(diethylaminoethyl ether) tris(ethyl iodide) ; 1,2,3-Tris(2-diethylaminoethoxy)benzene tris(ethyl iodide) and 2-[2,6-Bis(2-triethylazaniumylethoxy)phenoxy]ethyl-triethylazanium triiodide . Gallamine triethiodide ,which was developed by Daniel Bovet in 1947, is storage at 2-8 °C, soluble in water with 100 mg/mL. And it belongs to product categories such as Organics; Cholinergics; Antagonists and so on, it is white or milky white crystalline powder. 

Used as a synthetic nondepolarizing blocking drug, the actions of gallamine triethiodide are similar to those of tubocurarine, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output.It is also commonly used to stabilize muscle contractions during surgical procedures. Besides, Gallamine triethiodide is a non-depolarising muscle relaxant, which acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. In addition, first make focus of gallic acid, under the action of Sodium acetate , into the salt, and then with Diethylamino ethyl ethane and Iodine ethane to get Gallamine triethiodide.

The Gallamine triethiodide has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension and very high doses cause histamine release. It should be used cautiously in patients at risk from increased heart rate but may be preferred for patients with bradycardia. And Gallamine triethiodide is poison by ingestion, subcutaneous, intravenous, parenteral, intraduodenal, intraperitoneal, and intramuscular routes. When heated to decomposition it emits very toxic fumes of NH₃, NO_x, and I^-. Furthermore, it is harmful if swallowed and irritating to eyes, respiratory system and skin. So you should wear suitable protective clothing in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. The toxicity of Gallamine triethiodide as follows: