| Identification | |
| Name: | ketoconazole |
| Synonyms: | cis-1-acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1h-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine; |
| CAS: | 65277-42-1 |
| EINECS: | 265-667-4 |
| Molecular Formula: | C26H28Cl2N4O4 |
| Molecular Weight: | 531.44 |
| InChI: | InChI=1/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 |
| Molecular Structure: |  |
| Properties | |
| Transport: | UN 2811 |
| Density: | 139.11 cm3 |
| Stability: | Stable at room temperature in closed containers under normal storage and handling conditions. |
| Solubility: | Insoluble |
| Appearance: | white to off white crystalline powder |
| Packinggroup: | III |
| Biological Activity: | Antifungal agent; potent inhibitor of cytochrome P450c17. |
| Color: | white to light yellow |
| Usage: | Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor |
| Safety Data | |
| Hazard Symbols |
T:Toxic
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