| Identification | |
| Name: | Colforsin |
| Synonyms: | 1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,[3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)]-;(-)-Forskolin;Coleonol;ForsLean;HL 362;NSC 357088;NSC 375489; |
| CAS: | 66575-29-9 |
| EINECS: | 266-410-9 |
| Molecular Formula: | C22H34O7 |
| Molecular Weight: | 410.50116 |
| InChI: | InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1 |
| Molecular Structure: | ![(C22H34O7) 1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pen...](https://img1.guidechem.com/chem/e/dict/24/66575-29-9.jpg) |
| Properties | |
| Density: | 1.23 g/cm3 |
| Refractive index: | 1.551 |
| Water Solubility: | DMSO: 5 mg/mL stable at least 6 months at room temperature |
| Solubility: | DMSO: 5 mg/mL stable at least 6 months at room temperature |
| Appearance: | Colorless Crystalline Solid |
| Biological Activity: | Cell-permeable activator of adenylyl cyclase. Hypotensive and vasodilatory agent. Induces neuronal differentiation in stem cells and in several neuroblastoma. Also available as part of the PKA Tocriset™ . |
| Storage Temperature: | −20°C |
| Color: | off-white |
| Usage: |
1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,(3R,4aR,5S,6S,6aS,10S,10aR,10bS)- (CAS NO.66575-29-9 ) is used as possessing vasodilating and cardiostimulatory properties. |
| Safety Data | |
| Hazard Symbols |
Xn: Harmful
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