Home >> Chemicals Listing >> hot product list by 1  

19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-, (17a)- (68-23-5)

Identification
Name:19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-, (17a)-
Synonyms:19-Nor-17a-pregn-5(10)-en-20-yn-3-one,17-hydroxy- (6CI,8CI); 13-Methyl-17-ethynyl-17-hydroxy-1,2,3,4,6,7,8,9,11,12,13,14,16,17-tetradecahydro-15H-cyclopenta[a]phenanthren-3-one;17-Hydroxy-19-nor-17a-pregn-5(10)-en-20-yn-3-one; 17a-Ethinyl-17b-hydroxy-D5(10)-estren-3-one; 17a-Ethynyl-17-hydroxy-5(10)-estren-3-one; 17a-Ethynyl-17b-hydroxy-5(10)-estrene-3-one; 17a-Ethynyl-17b-hydroxy-D5(10)-estren-3-one; 17a-Ethynylestr-5(10)-ene-17b-ol-3-one; 17a-Ethynylestra-5(10)-ene-17b-ol-3-one; 17b-Hydroxy-19-nor-17a-pregn-5(10)-en-20-yn-3-one;3-Oxo-17b-hydroxy-17a-ethynyl-5(10)-estrene; Enidrel;NSC 15432; Norethinodrel; Norethynodrel; Noretynodrel; SC 4642
CAS:68-23-5
EINECS: 200-682-1
Molecular Formula: C20H26 O2
Molecular Weight: 298.46
InChI: InChI=1/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,16-18,22H,4-12H2,2H3/t16?,17?,18?,19-,20-/m0/s1
Molecular Structure: (C20H26O2) 19-Nor-17a-pregn-5(10)-en-20-yn-3-one,17-hydroxy- (6CI,8CI); 13-Methyl-17-ethynyl-17-hydroxy-1,2,3,4...
Properties
Melting Point: 169-170 deg C
Flash Point: 188.2°C
Boiling Point: 441.6°C at 760 mmHg
Density:1.15g/cm3
Refractive index:1.577
Solubility:PRACTICALLY INSOL IN WATER; SOL IN ACETONE & METHANOL; SOL @ 25 DEG C IN: 95% ETHANOL (1 IN 30), ETHER (1 IN 60), CHLOROFORM (1 IN 7)
Very slightly soluble in water; freely soluble in chloroform; soluble in acetone; sparingly soluble in ethanol.
VERY SLIGHTLY SOL IN SOLVENT HEXANE
Specification:

Descriptors Computed from Structure about Norethynodrel(CAS NO.68-23-5) is:
Canonical SMILES: CC12CCC3C(C1CCC2(C#C)O)CCC4=C3CCC(=O)C4
Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C3CCC(=O)C4
InChI: InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,16-18,22H,4-12H2,2H3/t16-,17-,18+,19+,20+/m1/s1
InChIKey: ICTXHFFSOAJUMG-SLHNCBLASA-N

Report:

IARC Cancer Review: Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 21 , 1979,p. 461.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 6 , 1974,p. 191.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Flash Point: 188.2°C
Color: Crystals from aq methanol
White, crystalline
Usage:The compound is a progestin used in Enovid, an oral contraceptive, also used in the treatment of endometriosis and hypermenorrhea.
Safety Data
 

Other Product