| Identification |
| Name: | Butanamide,N-cyclohexyl-4-[(1,2-dihydro-2-oxo-6-quinolinyl)oxy]-N-methyl- |
| Synonyms: | Cilostamide;OPC 3689; |
| CAS: | 68550-75-4 |
| Molecular Formula: | C20H26N2O3 |
| Molecular Weight: | 342.43204 |
| InChI: | InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23) |
| Molecular Structure: |
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| Properties |
| Transport: | 3249 |
| Density: | 1.18 g/cm3 |
| Refractive index: | 1.585 |
| Water Solubility: | Soluble in DMSO. |
| Solubility: | Soluble in DMSO. |
| Appearance: | White to off-white solid. |
| Packinggroup: | III |
| Biological Activity: | Selective inhibitor of type III phosphodiesterase (PDE3). Displays moderate selectivity for PDE3A isozyme vs. PDE3B (IC 50 values are 0.027 and 0.050 μ M for PDE3A and PDE3B respectively). Inhibits ADP-induced platelet aggregation (IC 50 = 16.8 μ M); anti-thrombotic. Also available as part of the Phosphodiesterase Inhibitor Tocriset™ . |
| Storage Temperature: | 0-6°C |
| Safety Data |
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