| Identification |
| Name: | Benzonitrile,2-[2-hydroxy-3-[[2-(1H-indol-3-yl)-1,1-dimethylethyl]amino]propoxy]- |
| Synonyms: | Bucindolol;DL-Bucindolol; MJ 13105-1 |
| CAS: | 71119-11-4 |
| Molecular Formula: | C22H25 N3 O2 |
| Molecular Weight: | 363.45 |
| InChI: | InChI=1/C22H25N3O2/c1-22(2,11-17-13-24-20-9-5-4-8-19(17)20)25-14-18(26)15-27-21-10-6-3-7-16(21)12-23/h3-10,13,18,24-26H,11,14-15H2,1-2H3 |
| Molecular Structure: |
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| Properties |
| Flash Point: | 319.9°C |
| Boiling Point: | 605.3°C at 760 mmHg |
| Density: | 1.21g/cm3 |
| Refractive index: | 1.632 |
| Biological Activity: | Non-selective β -adrenoceptor antagonist with additional α 1 -adrenoceptor blocking activity. K i values are 1.61, 1.20 and 68.9 nM for β 1 -, β 2 - and α 1 -adrenoceptors respectively. Also acts as a weak 5-HT 2A/2B antagonist. Displays vasodilatory and antihypertensive actions. |
| Flash Point: | 319.9°C |
| Safety Data |
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