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5-Pyrimidinamine,4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl- (75438-57-2)

Identification
Name:5-Pyrimidinamine,4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-
Synonyms:2-(6-Chloro-4-methoxy-2-methylpyrimidin-5-ylamino)-2-imidazoline;BDF 5895;BE 5895;Cynt;LY 326869;Lomox;Moxon;Moxonidine;Norcynt;Normoxocin;Nucynt;Physiotens;
CAS:75438-57-2
Molecular Formula: C9H12ClN5O
Molecular Weight: 241.68
InChI: InChI=1/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15)
Molecular Structure: (C9H12ClN5O) 2-(6-Chloro-4-methoxy-2-methylpyrimidin-5-ylamino)-2-imidazoline;BDF 5895;BE 5895;Cynt;LY 326869;Lom...
Properties
Flash Point: 174.3°C
Boiling Point: 364.7°C at 760 mmHg
Density:1.52 g/cm3 (20 C)
Refractive index:1.68
Solubility:Soluble
Appearance:crystal
Specification:

Cautions:?Moxonidine (CAS NO.75438-57-2)?should not be used for treatment in?patients with moderate to severe renal impairment. Abrupt discontinuation of the drug should also be avoided. If concomitant treatment with a beta blocker has to be stopped, the beta blocker should be discontinued first, then moxonidine after a few days.

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Drug interactions: It?is not indicated that concomitant administration of moxonidine and a thiazide diuretic such as hydrochlorothiazide, as both drugs' hypotensive effects may be enhanced.
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Side-effects: Noteworthy side effects?are as follows:?dry mouth, headache, fatigue, dizziness, nausea, sleep disturbances (rarely sedation), asthenia, vasodilatation, and rarely, skin reactions.

Flash Point: 174.3°C
Storage Temperature: Store in original container in a cool dark place.
Usage:

Antihypertensive,.

Safety Data
 

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