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2-Amino-3-methylimidazo(4,5-f)quinoline (76180-96-6)

Identification
Name:2-Amino-3-methylimidazo(4,5-f)quinoline
Synonyms:2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline;2-Amino-3-methylimidazo[4,5-f]quinoline;3-Methyl-3H-imidazo[4,5-f]quinolin-2-amine;IQ;
CAS:76180-96-6
Molecular Formula: C11H10N4
Molecular Weight: 198.2239 [g/mol]
InChI: InChI=1/C11H10N4.BrH/c1-15-9-5-4-8-7(3-2-6-13-8)10(9)14-11(15)12;/h2-6H,1H3,(H2,12,14);1H
Molecular Structure: (C11H10N4) 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoline;2-Amino-3-methylimidazo[4,5-f]quinoline;3-Methyl-3H-imid...
Properties
Density:1.41 g/cm3
Solubility:Soluble in methanol, ethanol, and dimethyl sulfoxide.
Appearance:light tan crystalline solid or tan powder
Specification:

 2-Amino-3-methylimidazo(4,5-f)quinoline , its cas register number is 76180-96-6. It also can be called 2-Amino-3-methyl-3H-imidazo(4,5-f)quinoline ; 3-Methyl-3H-imidazo(4,5-f)quinolin-2-amine ; IQ ; 3H-Imidazo(4,5-f)quinolin-2-amine, 3-methyl- .It is a light tan crystalline solid or tan powder.It is highly mutagenic in the Ames test. Investigations have shown that this compound may be present in broiled fish, fried beef, commercial beef extracts and protein pyrolysates.It is sensitive to light and air and insoluble in water. It may be sensitive to prolonged exposure to heat. It is stable under moderately acidic and alkaline conditions and in cold dilute aqueous solutions when protected from light.It is rapidly degraded by dilute hypochlorite.

Report:

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 56 (1993),p. 165.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 (1986),p. 261.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 56 (1993),p. 165.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 (1986),p. 261.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 56 (1993),p. 165.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Storage Temperature: Refrigerator
Color: Crystalline solid
Usage:IQ is highly mutagenic in the Ames test. Investigations have shown that this compound may be present in broiled fish, fried beef, commercial beef extracts and protein pyrolysates
Safety Data
Hazard Symbols T: Toxic