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2,5-Cyclohexadiene-1,4-dione,2-[2-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]- (78860-34-1)

Identification
Name:2,5-Cyclohexadiene-1,4-dione,2-[2-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]-
Synonyms:2,5-Cyclohexadiene-1,4-dione,2-[2-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-butenyl)-1H-indol-3-yl]-(9CI); Demethylasterriquinone B 1; L 783281
CAS:78860-34-1
Molecular Formula: C32H30 N2 O4
Molecular Weight: 506.59
InChI: InChI=1/C32H30N2O4/c1-6-32(4,5)31-23(20-11-7-8-13-22(20)34-31)25-29(37)27(35)24(28(36)30(25)38)21-16-33-26-18(15-14-17(2)3)10-9-12-19(21)26/h6-14,16,33-35,38H,1,15H2,2-5H3
Molecular Structure: (C32H30N2O4) 2,5-Cyclohexadiene-1,4-dione,2-[2-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-met...
Properties
Flash Point: 425.6°C
Boiling Point: 780.2°C at 760 mmHg
Density:1.335g/cm3
Refractive index:1.72
Biological Activity: Selective insulin receptor (IR) activator/mimetic (EC 50 values are 3-6 μ M for IRTK and 100 μ M for IGF1R and EGFR). Increases IR β subunit tyrosine phosphorylation and downstream activation of PI 3-kinase and Akt, but not ERK. Induces glucose uptake in adipocytes and skeletal muscle in vitro , without enhancing vascular proliferation. Binds GAPDH.
Flash Point: 425.6°C
Safety Data
 

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